Among these are giantcell tumor of the synovia, xanthoma, hemorrhagic villous synovitis, sclerosing hemangioma, xanthogranuloma, pigmented giantcell xanthosarcoma, benign synovioma, and pigmented villonodular synovitis. Report of 52 cases surgically and histologically controlled. Pigmented villonodular synovitis pvns oxford university hospitals. Pigmented villonodular synovitis is a proliferative dis. Pigmented villonodular synovitis is a proliferative condition of the synovium. The lesion is always monoarticular, the knee joint being by far the most common location. In 1852, it was described by chassaignac apud byers et al. It is characterized by a noncancerous mass or tumor. Pigmented villonodular synovitis is a disease of unknown etiology that mainly develops in the.
Experimental production of pigmented villonodular synovitis. It rarely involves multiple joints and often recurs after surgery. Localized tgct is sometimes referred to as localized pigmented villonodular synovitis l pvns, giant cell tumor of the tendon sheath gctts, nodular tenosynovitis, localized nodular tenosynovitis, and ltgct 1. Pigmented villonodular synovitis in type 1 diabetes mellitus. It doesnt spread or travel to other parts of the body. Pigmented villonodular synovitis pvns is a benign, locally invasive synovial proliferation of unknown etiology affecting joints, bursae, and tendon sheaths. Arthroscopic surgical treatment of pigmented villonodular. Pigmented villonodular synovitis in children springerlink. The literature is replete with reports of what we believe to be a single lesion of the synovial membrane described under various titles.
Pvns is characterized by hyperplasia of the synovium or tendon sheath, with notable proliferation of stromal cells, large quantities of intra and extracellular hemosiderin and. Postoperative management of pigmented villonodular synovitis. Pigmented villonodular synovitis pvns describes a rare disease caused by an abnormal proliferation of the synovial membrane in large and small joints. Pigmented villonodular synovitis pvns, also known as diffusetype tenosynovial giant cell tumor or tgct is a joint disease characterized by inflammation and overgrowth of the joint lining. The localized form is characterized by focal involvement of the synovium, with either nodular or pedunculated masses.
Pigmented villonodular synovitis orthopaedic web links. Pigmented villonodular synovitis tenosynovitis, bursitis1 is a hyperplastic production of synovial tissue of the joints, the tendinous sheaths, the mucous bursae, or the fibrous tissue adjacent to. Pigmented villonodular synovitis pvns is an aggressive proliferative lesion that usually involves the synovial tissues of big joints. J pigmented villonodular synovitis, bursitis, and tenosynovitis. Sinovitis pigmentada vilonodular pvns e uma lesao do tecido sinovial e raramente e encontrada na coluna vertebral.
Several cases of bilateral diffuse pigmented villonodular synovitis pvns or. Pigmented villonodular synovitis and giant cell tumors of the tendon sheath. Pigmented villonodular synovitis diagnostic delay due to. Pigmented villonodular synovitis pvns is a proliferation of the syn ovium that leads to villous or nodular changes of synoviallined joints, bursae and tendon sheaths. Pigmented villonodular synovitis pvns is a rare lesion that appears as a proliferative process, affecting the synovial joints, tendon sheaths, and bursal membranes. Pvns may have no symptoms, or may present as pain, stiffness, or swelling in a joint, with locking and instability 2. Pigmented villonodular synovitis giantcell tumor of the tendon sheath and synovial membrane.
Diffuse pigmented villonodular synovitis in knee joint. Pigmented villonodular synovitis diagnostic delay due to coexistence with ankylosing spondylitis. Monoarticular involvement, the most common process, occurs in two forms. Pvns is a benign disorder of unknown etiology, characterized by idiopathic proliferation affecting the synovium of joints, tendon sheaths, and bursae. Rehabilitation outcome of a case of pigmented villonodular. Pvns is most commonly monoarticular 70% knee joint but occasionally it can be oligoarticular. Pigmented villonodular synovitis is a rare disease, but it involves the knee in 80% of the cases. Radiation therapy has reemerged as an additional treatment method for pigmented. Diffuse tgct is sometimes referred to as pigmented villonodular synovitis pvns, conventional pvns, and dtgct 1. Each case of pvns is usually characterized by its site of origin and by its form of growth. Clinical, pathologic, andradiologic features robert h.
Jan 02, 2020 pigmented villonodular synovitis pvns is a disease in which the tissue lining the joints and tendons in the body synovium grows abnormally. Pigmented villonodular synovitis pvns is a rare benign proliferative condition affecting synovial membranes of joints, bursae or tendons resulting from possibly neoplastic synovial proliferation with villous and nodular projections and hemosiderin deposition. Radiological features of pigmented villonodular synovitis and giant. However, it is much less common than in the metacarpophalangeal joint and is a rare primary cause of pain see chapter 36. Pigmented villonodular synovitis pvns is a rare, benign, inflammatory, proliferative disorder of synovium. Peter f m choong,helena willen, mef nilbert, fredrik mertens, nils mandahl, birgitta carlen and anders rydholm we report a 48 year followup of a case of recurrent pigmented villonodular synovitis of the knee. Unusual presentation of pigmented villonodular synovitis of.
Pigmented villonodular synovitis pvns is a disease in which the tissue lining the joints and tendons in the body synovium grows abnormally. All the cases met strict histologic criteria for diagnosis. The authors present a series of seven case reports of localized pigmented villonodular synovitis lpvns treated by arthroscopy resection between june of 1994 and october of 2001. Pigmented villonodular synovitis pvns is a condition that causes the synoviumthe thin layer of tissue that lines the joints and tendonsto thicken and overgrow. Pigmented villonodular synovitis pvs is a rare disease of the synovial layer in joints, seen particularly in children. Pigmented villonodular synovitis pvns is a rare clinical entity with higher incidence in women 3.
Al sayed r al attar, pigmented villonodular synovitis pvns in human and animals. It affects in decreasing order of frequency the knee, hip, ankle, and shoulder, while elbows are rarely involved. Pigmented villonodular synovitis pvns is a synovial proliferation disorder that remains a diagnostic difficulty because of its nonspecific presentation and subtle. Pigmented villonodular synovitis pvns of the knee joint. Postoperative management of pigmented villonodular. The hip is a rare site of appearance, being involved in only 15% of all cases. In this article, symptoms, clinical findings, and the diagnosis procedure are reported in a rare case of. May 26, 2020 pigmented villonodular synovitis is a benign, locally aggressive disorder of joints, bursae and tendon sheaths. Pigmented villonodular synovitis pvns everything you. Pigmented villonodular synovitis of the thoracic spine.
Pdf articular pigmented villonodular synovitis of the mp. Pvns is a rare neoplasticlike pathological entity of unknown etiology affecting the synovium of the joint, tendon or bursa. Pigmented villonodular synovitis pvns is a benign and uncommon clinical entity, characterized by excessive proliferation of synovial membrane of joints, tendon sheaths and bursas. Surgical treatment of diffuse pigmented villonodular synovit. Pigmented villonodular synovitis radiology reference.
Review pigmented villonodular synovitis ofsynovialjoints. Is pigmented villonodular synovitis of the knee hereditary. When a patient has pigmented villonodular synovitis. Both pigmented villonodular synovitis as well as giant cell tumor of the tendon sheath are considered. The pigmented villonodular synovitis pvns is a very uncommon nonmalignant, but proliferative disease, eventually with locally aggressive behavior, that can affect synoviallined joints, bursae. Pigmented villonodular synovitis of the hip and knee. Pigmented villonodular synovitis pvns is an uncommon proliferative disorder of the synovium, with an annual incidence of 1. Pigmented villonodular synovitis monoclonality and metastasis a case for neoplastic origin. Both pigmented villonodular synovitis as well as giant cell tumor of the tendon sheath are considered similar from the point of view of the histological. Pigmented villonodular synovitis of the temporomandibular joint presenting as a middle cranial fossa tumor. At the baseline evaluation, symptoms ranged from diffuse pain to localized swelling of the knee, with or without mechanical blockage of the joint.
Theopinions orassertions contained hereinare theprivateviewsoftheauthors andarenottobe. This is an epidemiological trial in order to determine the frequency of pigmented villonodular synovitis in a series of 1,150 arthroscopic procedures of the knee, for diagnosis and treatment for either traumatic or. It mainly affects young adults and is equally distributed between. Pigmented villonodular synovitis pvns is a benign proliferative disorder that affects synoviallined joints, bursae, and tendon sheaths. A learnercentric tool for radiology knowledge tracking. Pigmented villonodular synovitts, tenosynovitis, bursitis.
It is said that the estimated incidence of pvns is around 1. Pigmented villonodular synovitis of the temporomandibular. Pigmented villonodular synovitis pvns was first defined by jaffe et al 1941 as a monoarticular inflammatory disease of uncertain pathogenesis, and its clinical, radiographic and histological aspects have been repeatedly described by several authors campanacci et al, 1972. Pigmented villonodular synovitis genetic and rare diseases. Localized pigmented villonodular synovitis of the knee. Villonodular synovitis an overview sciencedirect topics. A discussion of the synovial and bursal equivalents of the tenosynovial lesion commonly denoted as xanthoma, xanthogranuloma, giant cell tumor or myeloplaxoma of the tendon sheath, with some consideration of the tendon sheath lesion itself. Pigmented villonodular synovitis of joints, on the other hand, is a rare complaint.
In order to achieve an optimal result of treatment it is necessary to carry out specific diagnostics and a targeted therapy approach. The optimal surgical treatment for diffuse pigmented villonodular synovitis is still a matter for debate, with combined anterior arthroscopic and open posterior excision being considered the preferred method. The intra articular disease may be localized or diffuse. Benign in this case means that the condition is confined to the area of involvement. Pigmented villonodular synovitis of the knee in a patient on oral anticoagulation therapy. May 12, 1989 pigmented villonodular synovitis is a nonneoplastic proliferation of synovial tissue.
Pigmented villonodular synovitis treatment pvns surgery. Pigmented villonodular synovitis pvns is a rare proliferative disorder that affects the synovium in young and middleaged adults. The mass or tumor that results from this overgrowth is not cancerous and does not spread metastasize to other areas of the body. Three primary types are recognized, which include the more common diffuse, villous, pigmented form that affects the synovial lining of the entire joint. Burnett fromthe university ofglasgow, departmentofpathology. Although most believe that it is an inflammatory process, some. Grimer, pigmented villonodular synovitis of the foot and ankle. Ebraheims educational animated video describes the conditon of pigmented villonodular synovitis pvns. Some of the most highly categorized items include an entry lymphoma with 46 categories, an entry tb with 31 categories, an entry.
Articular involvement is usually in a weight bearing extremity, most often the knee. Extended pigmented villonodular synovitis of the hand. Unusual presentation of pigmented villonodular synovitis. It does not cause death but disability is possible. Apr 04, 2016 pigmented villonodular synovitis pvns is a disease in which the tissue lining the joints and tendons in the body synovium grows abnormally. Early diagnosis allows treatment with resection of the affected synovial tissue, avoiding secondary osteoarthritic lesions of the normally unaffected joint structures. Pigmented villonodular synovitis pvns is a benign disease of the joint synovium.
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